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Separation of Related Impurities from Vercuronium Bromide as per BP monograph. Be the first to rate this application


The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of Vercuronium Bromide. The separation was performed on a Thermo Scientific Acclaim Polar Advantage-II HPLC column using the method described in BP monograph. The results obtained for Resolution exceeded the criteria stated in the BP. Resolution between Vercuronium Bromide and Impurity-C was 8.97 ( met BP criteria of NLT 1.2), Resolution between Vercuronium Bromide and Impurity-F was 2.15 (met BP criteria of NLT 1.2) and Resolution between Vercuronium Bromide and Impurity-B was 10.78 (met BP criteria NLT 2.0).
Market: Pharma
Keywords: HPLC, UV detection, Acclaim Polar Advantage-II, Vercuronium Bromide
Matrix: N/A
Author: Manish Singh
Affiliation: Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India
Uploaded on 9/28/2016.

For Research Use Only. Not for use in diagnostic procedures.