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Displaying 1-5 of 11 results for Tag: excipient
Analyzing Residual Solvents in Pharmaceutical Products Using GC Headspace with Valve-and-Loop SamplingInstrument Type: GC
This application note describes the analysis of residual solvents in accordance with USP method <467> using the Thermo Scientific™ TRACE™ 1310 GC, the new Thermo Scientific™ TriPlus™ 300 Headspace autosampler, and the Thermo Scientific™ Dionex™ Chromeleon™ chromatography data system (CDS) software. The method details the chromatographic system and analytical conditions to be used and addresses the acceptable limits for each solvent.
Determination of Hoodigosides by UHPLC-CAD on VanquishInstrument Type: Unspecified
This application highlights the complimentary sensitivity of UHPLC with charged aerosol and diode array detection for determination of hoodigosides in plant extracts and dietary supplements. Eight oxypregnane steroidal glycosides isolated from dried plant material are separated from one another and from excipients such as stearic acid within 20 min on a Thermo Scientific™ Vanquish ™ UHPLC system paired with a Thermo Scientific™ Vanquish™ C18 analytical column and detected by both charged aerosol and UV/Vis diode array detectors.
Simple isocratic method for the analysis of doxorubicin injetion by HPLC with RI detectionInstrument Type: HPLC
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of doxorubicin injection. The separation was performed on a Thermo Scientific Accucore XL C18 HPLC column with RI detection.
Accurate determination of l-methyltetrahydrofolate calcium in formulation using reversed-phase HPLC-UVInstrument Type: HPLC
The Thermo Scientific Dionex Ultimate 3000 system is applied for the analysis of a l-methyltetrahydrofolate in solid dosage formulations. The separation is performed on a Thermo Scientific Accucore C8 HPLC column in less than 20 minutes, with UV detection at 280 nm.
Determination of glimepiride in formulation using a polar endcapped UHPLC columnInstrument Type: UHPLC
The Thermo Scientific Dionex UltiMate 3000 system is applied for the determination of glimepiride in tablet formulation. The Thermo Scientific Hypersil GOLD aQ UHPLC column separates glimepiride from the excipients present in the formulation in less than 11 minutes.