Forensic Screening for Drugs in Urine Using High-Resolution MS/MS Spectra and Simplified High-Performance Screening Software

Instrument Type: LCMSMS

Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.

Quantitation of 122 Drugs in Urine by Triple Quadrupole Mass Spectrometry

Instrument Type: LCMSMS

Forensic toxicologists face an ever-expanding list of compounds for analysis. This note presents work done using a next-generation triple quadrupole mass spectrometer with fast SRM acquisition speed for quantitation of 122 analytes in a single chromatographic run, where scan speed does not impact sensitivity or quantitative performance. Compounds analyzed include opiates, opioids, benzodiazepines, barbiturates, amphetamines, tricyclic antidepressants, illicit compounds, and more. For forensic use only.

Fast analysis of purines and pyrimidines by ultra high temperature LC

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of purines and pyrimidines. The separation is performed on a Thermo Scientific Hypercarb column, with an ultra high temperature gradient.

Improved analysis of xanthines using a Thermo Scientific Hypersil GOLD aQ HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of xanthines. The separation is performed on a Thermo Scientific Hypersil GOLD aQ HPLC column, with UV detection at 254 nm.