AN108:Determination of Transition Metals in Serum and Whole Blood by Ion Chromatography

Instrument Type: IC

The determination of transition metals in physiological fluids is of considerable interest in clinical chemistry. This application note describes an attractive alternative to traditional spectroscopic methods by using the principles of ion exchange. Separation between individual metals can be enhanced or altered simply by changing eluents (pyridine-2, 6-dicarboxylic acid or oxalic acid). This figure illustrates the selectivity on an IonPac CS5A column when using a pyridine-2, 6-dicarboxylic acid eluent.

AN131: Determination of Transition Metals at PPT Levels in High-Purity Water and SC2 (D-clean) Baths

Instrument Type: IC

Semiconductor cleaning solutions used to remove potentially damaging transition metal contamination are monitored to assess cleaning efficiency. Here trace concentrations (ng/L) of transition metals in semiconductor cleaning solutions and deionized water are separated using the strong complexing agent, pyridine-2,6-dicarboxylic acid (PDCA), on an IonPac CS5A column optimized with anion- and cation-exchange chemistry. Then a post-column derivitization agent, 4-(2- pyridilazo)resorcinol (PAR), is added to displace PDCA and to facilitate detection at 520–530 nm.

AN69: Determination of Aluminum in Complex Matrices Using Chelation Ion Chromatography

Instrument Type: IC

Determination of trace metals in complex matrices has been a difficult analytical challenge. This application note describes the extension of Chelation ion chromatography for the analytical determination of aluminum in complex matrices. This technique allows aluminum to be preconcentrated from matrices high in salts, acids, or bases. Following selective concentration, aluminum is eluted to a conventional cation exchange column for separation from other transition metals. Selective detection is accomplished using post-column derivatization with Tiron and subsequent UV detection at 310 nm.

AN158: Determination of Trace Sodium and Transition Metals in Power Industry Samples by Ion Chromatography with Nonsuppressed Conductivity Detection

Instrument Type: IC

This application compares suppressed to nonsuppressed conductivity detection for the determination of sub-ppb concentrations of sodium in simulated power plant matrices. Linearity, limits of detection, and recovery of sub-ppb sodium spiked into simulated samples containing high concentrations of ethanolamine are reported. In addition, this application describes the determination of transition metals by nonsuppressed conductivity detection.