The success of water fluoridation in preventing and controlling dental caries has led to the development of many fluoride- containing products. The determination of fluoride is critical to ensure that the labeled amount of fluoride is within specifications for quality control. Here, we describe an approach for determining fluoride using a Reagent-Free IC system with IonPac AS18 column in less than 15 min. This approach eliminates the need to manually prepare eluents and thereby increases the automation, ease-of-use, and reproducibility between analysts and laboratories.

The United States Food and Drug Administration (U.S. FDA) and regulatory agencies in other countries require that pharmaceutical products be tested for composition. This Application Note describes the use of two anion exchange columns with suppressed conductivity detection to analyze common anions in pharmaceutical formulations. Here demonstrate that the IonPac AS11 resolves, in the same injection, common inorganic anions such as fluoride, chloride, bromide, sulfate, nitrate, and phosphate, as well as common organic anions such as benzoate, sorbate, citrate, and saccharin.

The Thermo Scientific Acclaim Mixed-Mode WAX-1 column is used for the rapid analysis of soft drink ingredients, with UV detection at 210 nm. Due to the columns multi-functional chemistry, this assay can be performed in just 3 minutes.

The Thermo Scientific Acclaim Mixed-Mode WAX-1 column is used for the separation of ingredients in a toothache pain-reliever, with UV detection at 210 nm.

In this work, the baseline separation of three preservatives (sorbate, benzoate and benzisothiazolone) was achieved with excellent peak efficiency and peak shape with the Thermo Scientific Acclaim Mixed-Mode WAX-1 column.