This application brief demonstrates a method for detecting common organic acids using a Thermo Scientific™ Dionex™ Integrion™ HPIC™ system with a Thermo Scientific™ Dionex™ IonPac™ AS11-HC-4μm column set and coupled to a Thermo Scientific™ ISQ™ EC single quadrupole mass spectrometer.

Plastic samples can be very difficult to analyze as sample preparation is required to extract analytes or remove interfering matrices, and these sample preparation techniques can be labor intensive. In this application note, we demonstrate that a CIC system can be used for automated qualitative and quantitative analysis of halogens and sulfur in plastic samples. Four plastic samples were analyzed for their chlorine (Cl), bromine (Br), and sulfur (S) content. Method accuracy was evaluated using a polymer certified reference material (ERM EC680k) for Cl,Br, and S.

This work used the properties of the 4-μm-particle-size Dionex IonPac AS11-HC-4μm column, combined with the Thermo Scientific™ Dionex™ ICS-5000+ HPIC system, to produce a high-resolution separation of organic acids and inorganic anions in kombucha samples, enabling accurate determinations of those analytes. An ICS-6000 can be used for this application.

Before running any samples, Thermo Scientific recommends that you first confirm the performance of the column by reproducing the lot validation report chromatogram shipped with column. Compare your results with the one reported in the quality assurance report. At least three injections should be made. This record provides an eWorkflow for executing the QAR method on an ICS-5000 system.

Chromates are oxyanions of chromium in the oxidation state of +6. All Cr(VI) compounds are strong oxidizing agents that are considered toxic and potentially carcinogenic. The method described here uses suppressed conductivity detection for the determination of Cr(VI) in drinking water, thus eliminating the post column derivatization used in EPA Methods 218.6 and 218.7. This new approach uses either the Dionex IonPac AS11-HC or AS11-HC-4μm column to separate chromate from other anions in HIW. Even in the challenging HIW sample, the method can easily detect and quantify 2 μg/L Cr(VI).