To describe an accurate and precise high-throughput analytical technique for the analysis of testosterone, androstenedione, and 17-hydroxy progesterone utilizing micro-scale solid phase extraction (SPE), followed by liquid chromatography coupled with triple quadrupole mass spectrometry (LC-MS/MS). For research use only. Not for use in diagnostic procedures.

The Thermo Scientific HPLC system is applied for the determination of oxymorphone and its isomer from human plasma. The samples are prepared using Thermo Scientific HyperSep solid supported liquid-liquid extraction (SLE), and the separation performed using a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.

The methods here demonstrate the advantages of using the Thermo Scientific Dionex UltiMate 3000 system; alongside the Thermo Scientific TSQ Vantage with a Thermo Scientific Hypersil GOLD PFP 3 μm column for the separation and determination of Raloxifene and its glucuronide metabolites from human plasma with MS detection. For Research Use Only. Not for use in diagnostic procedures.

The Thermo Scientific Dionex UltiMate 3000 system was applied with the Thermo Scientific TSQ Vantage with a Thermo Scientific Accucore C18 2.6 μm column for the separation and determination of liposomal and non-liposomal (free) Doxorubicin from human plasma with MS detection. For Research Use Only. Not for use in diagnostic procedures.

The Thermo Scientific Dionex UltiMate 3000 system is applied alongside the Thermo Scientific TSQ Vantage for the determination of ethinyl estradiol in human plasma. The sample was prepared using Thermo Scientific SOLA SCX SPE, followed by separation on a Thermo Scientific Syncronis C18 1.7 μm HPLC column. For Research Use Only. Not for use in diagnostic procedures.