Determination of Different Classes of Pesticide Residues in Processed Fruits and Vegetables by LC-MS Using the TSQ Quantum Ultra According to EU Directive 91/414 EEC

Instrument Type: LCMSMS

A diet rich in fruits and vegetables is thought to reduce the risk of some types of cancer, circulatory, and heart disease. Commercially grown produce can contain high levels of pesticide residues that can lead to serious health problems when consumed. Due to growing public concern over the amount of pesticide residues in foods, the EU has enacted several directives including new 'active' ingredients entering the market to replace compounds banned by Directive 91/414/ EEC. We describe an LC-ESI-MS/MS method for the detection and quantification of 45 pesticides in various food matrices.

Sensitive and Accurate Quantitation of Perfluorinated Compounds in Human Breast Milk using Selected Reaction Monitoring Assays by LC/MS/MS

Instrument Type: LCMSMS

Perfluorinated compounds (PFCs) are ubiquitous and persistent pollutants that bioaccumulate in animals and humans. The potential toxicity of these chemicals has fueled efforts to develop robust analytical techniques for measuring low levels of PFCs in human matrices. We describe a quantitative selected reaction monitoring (SRM) assay developed for six PFCs using the Thermo Scientific TSQ Vantage triple-stage quadrupole mass spectrometer (MS) coupled to a PFC-free Thermo Scientific Accela LC system.

食品残留農薬35成分のLC/MS/MS分析

Instrument Type: LCMSMS

I近年、食の安全へ消費者の関心が高まるなか、食品の残留農薬検査においては、対象となる農薬の数が飛躍的に多くなってきています。また、2006年5月のポジティブリスト制導入により、一度に多成分の農薬を、迅速かつ正確に測定することが求められています。LC/MS/MSシステムはこのような夾雑物を多く含む試料から、選択的に目的化合物を高感度で定量する手法として、近年多くの実績をあげています。ここでは、LC/MS/MSを用いて、農薬35成分を一斉分析した結果をご紹介します。

On-line Enrichment HTLC/MS/MS Assay for Multiple Classes of Antibiotics in Environmental Water Sources

Instrument Type: LCMSMS

There is a growing concern over the presence of antibiotics in environmental sources of water. This has caused environmental and government labs to develop LC/MS methods to monitor water supplies for the presence of antibiotics. We developed a method to screen for antibiotics in surface water by applying on-line preconcentration and analyte extraction with LC/MS/MS detection.