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Displaying 1-4 of 4 results for Tag: Cholesterol drug
Separation of related impurities from Combination drug of Ezetimibe and Simvastatin
Instrument Type: HPLCThe Thermo Scientific Dionex UltiMate 3000 LC system is applied for the separation of related impurities separation of combination drug of Ezetimibe and simvastatin. The separation was performed on a Thermo Scientific Hypersil Gold PFP column with UV detection at 238 nm. With a total run time of 120 minutes the method allows separation of all related impurities of Ezetimibe and Simvastatin.
AN2967: Implementation of a Walk-Up High-Pressure Capillary Ion Chromatograph for the Fast Separation of Pharmaceutical Relevant Inorganic Cations (Cholesterol tablet)
Instrument Type: ICThe counter ion impacts the API drug’s efficacy, solubility, and toxicity, and therefore counter ion determinations are important to pharmaceutical companies during all stages of product development and as part of product quality monitoring. In this example, the calcium counter ion is determined in a water extract of a pharmaceutical drug tablet designed to treat high cholesterol serum levels. Here fast calcium determinations were demonstrated on IonPac CS12A-8µm capillary column using a walk-up high pressure capillary IC system.
An accurate related substances analysis of atorvastatin and ezetimibe using HPLC-UV
Instrument Type: HPLCThe Thermo Scientific Dionex Ultimate 3000 system is applied for the related substance analysis of atorvastatin and ezetimibe. The separation is performed on a Thermo Scientific Accucore PFP HPLC column, with UV detection at 260 nm.
Improved analysis of atorvastatin using a Thermo Scientific Hypersil GOLD Kappa column
Instrument Type: HPLCThe Thermo Scientific HPLC system is applied for the analysis of atorvastatin. The separation is performed on a Thermo Scientific Hypersil GOLD Kappa column, with UV detection at 254 nm.
