AN10451: Determination of Chlorophenols in Water According to U.S. EPA Method 528

Instrument Type: GCMS

Phenolic compounds are involved in many industrial processes as either reagents or byproducts. Their ubiquitous presence and widespread use makes pollution with phenols very likely. Waters are particularly impacted and monitoring is necessary to detect this source of pollution as it can represent a serious threat to environmental and human health. U.S. EPA method 528 provides guidelines for the GC-MS analysis of phenols in water. This application note provides a workflow method for determination of chlorophenols in drinking water and can be used for U.S. EPA Method 528.

Determination of Chlorophenols in Water according to US EPA Method 528

Instrument Type: GCMS

The application provides a complete analytical workflow for the GC-MS analysis of phenolic compounds in water according to the EPA 528 guideline. The method includes all the steps required to collect, prepare and analyze samples. The extraction and purification of the analytes have been achieved with the Thermo Scientific Dionex AutoTrace 280 SPE for complete unattended operations.

Analysis of phenol standards by EPA method 604

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of phenol standards by EPA method 604. The separation is performed on a Thermo Scientific Acclaim PolarAdvantage (PA) column, with UV detection at 285 nm.

Improved analysis of chlorophenols using a Thermo Scientific Hypersil GOLD PFP HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of chlorophenols. The separation is performed on a Thermo Scientific Hypersil GOLD PFP HPLC column, with UV detection at 230 nm