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Displaying 1-3 of 3 results for Tag: Cefepime
AN199: Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography SystemInstrument Type: IC
This application note describes a cation-exchange chromatography method that significantly reduces the time between injections relative to the current USP method (by approximately 3 h) due to the very low hydrophobic character of the IonPac® CS17 column, enabling a faster elution of strongly retained compounds (e.g., cefepime). The linearity, detection limits, precision, and recovery of NMP in cefepime hydrochloride are determined. The limit of quantitation for this method is approximately 0.001% NMP, well within the limit of 0.3% set in the USP method.
Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography SystemInstrument Type: IC
This application describes a cation-exchange chromatography method for the determination of N-methylpyrrolidine (NMP) in Cefepime using the Thermo Scientific Dionex IonPac CS17 column and suppressed conductivity detection.
Improved analysis of cefepime and related substances using a Thermo Scientific Acclaim 120 C18 HPLC columnInstrument Type: HPLC
The Thermo Scientific UltiMate 3000 HPLC system is applied for the determination of cefepime and related substances. The separation is performed on a Thermo Scientific Acclaim 120 C18 HPLC column, with UV detection at 254 nm.