Assay analysis of Albuterol Sulphate as per USP 40 Monograph

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for Assay analysis of Albuterol sulphate as per USP. The analysis was performed on a Thermo Scientific Hypersil Gold CN HPLC column using the method described in the USP 40 monograph. The results obtained for resolution met the criteria as per USP. The results obtained for the resolution between Albuterol sulphate & Albuterol Impurity A was 4.26 (USP criteria is NLT 1.5). RSD for replicate injections were found to be 0.68 & 1.14 forAlbuterol sulphate & Albuterol Impurity A respectively (USP criteria is NLT 1.5%).

Forensic Screening for Drugs in Urine Using High-Resolution MS/MS Spectra and Simplified High-Performance Screening Software

Instrument Type: LCMSMS

Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.

Quantification of EPA 1694 Pharmaceuticals and Personal Care Products in Water at the ng/L Level Utilizing Online Sample Preparation with LC-MS/MS

Instrument Type: LCMSMS

There is growing environmental concern regarding the health impact of trace levels of pharmaceuticals and personal care products (PPCPs) in water resources. In response, the U.S. Environmental Protection Agency (EPA) published Method 1694, which determines dozens of PPCPs in water, soil, sediment, and biosolids by HPLC-MS/MS. We demonstrate a progressive approach to analyzing PPCPs in environmental sources of water at the ng/L level with online sample preparation using small volumes of water, thus saving time and reducing the cost of analysis.

Fast analysis of salmeterol xinafoate using a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of salmeterol xinafoate. The separation is performed on a Thermo Scientific Hypersil GOLD HPLC column, with UV detection at 254 nm.