Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.

There is growing environmental concern regarding the health impact of trace levels of pharmaceuticals and personal care products (PPCPs) in water resources. In response, the U.S. Environmental Protection Agency (EPA) published Method 1694, which determines dozens of PPCPs in water, soil, sediment, and biosolids by HPLC-MS/MS. We demonstrate a progressive approach to analyzing PPCPs in environmental sources of water at the ng/L level with online sample preparation using small volumes of water, thus saving time and reducing the cost of analysis.

The Thermo Scientific Acclaim Organic Acid column is used for the analysis of bromide and organic acids present in cough syrup. Sample preparation was performed using Thermo Scientific Dionex OnGuard II P cartridges.

The separation of four active ingredients in cough syrup was performed on a Thermo Scientific Acclaim PolarAdvantage (PA) 3 µm column with UV detection.

The Thermo Scientific Acclaim Mixed-Mode WAX-1 column is used for the separation of active ingredients in a cough syrup, with UV detection at 210 nm. The Thermo Scientific Acclaim Mixed-Mode WAX-1 column resolves the active ingredients under simple isocratic conditions.