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Displaying 1-5 of 10 results for: lc-ms

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Forced-degradation evaluation of erythromycin by HPLC and single quadrupole mass spectrometry

Instrument Type: LCMS

Simple stability-indicating LC-MS method for erythromycin. Compare the impurity profiles of an erythromycin reference standard with stressed analyte.

Impurity profiling of the synthetic peptide LL-37 using high-performance liquid chromatography with combined UV and single quadrupole mass spectrometric detection

Instrument Type: LCMS

Leveraging UV detection for the determination of the impurity levels and mass detection for identification of the active pharmaceutical ingredient (API) and other product related impurities using a rapid method for synthetic peptide impurity profiling

Oligonucleotide characterization for quality control and increased productivity by single quadrupole mass spectrometer with extended mass range

Instrument Type: LCMS

We demonstrate increased productivity in the analysis of synthetic oligonucleotides between 29 and 40 base pairs in length by incorporating the Thermo Scientific ISQ EM single quadrupole mass spectrometer into a UV-based quality control method

Achieve confident synthesis control with the Thermo Scientific ISQ EC single quadrupole mass spectrometer

Instrument Type: LCMS

Demonstrate quantitative synthesis control with the Thermo Scientific ISQ EC single quadrupole mass spectrometer and show its benefit for medicinal chemistry.

How to Realize LC-MS Quantitation with Chromeleon 7.2 CDS

Instrument Type: LCMS

Chromeleon 7.2 CDS supports a quantitative method for targeted analysis of antibiotics with LC coupled to both UV and MS detection. The application is realized with state-of-the-art LC-MS instrumentations. The Thermo Scientific Vanquish UHPLC system is coupled to the Thermo Scientific Q Exactive HF Hybrid Quadrupole-Orbitrap mass spectrometer. Here we present step-by-step the creation of the instrument method, data processing method, and report template, that are thereafter used to generate an LC-MS eWorkflow.