An ion chromatography-mass spectrometry (IC-MS) method to meet the analytical need of understanding the sample composition and degradation byproduct in simulated battery electrolytes. Integrating an organic solvent gradient, this method achieves excellent separation of many analytes allowing lithium-ion battery (LIB) manufacturers and researchers to gain knoledge to improve quality assurance, quality control and failure analysis processes to ensure the battery's performance.
This work describes the use of Dionex IonPac AS28-Fast-4μm column that was designed specifically for the trace analysis of inorganic anions and monovalent organic acids. Improved peak efficiencies in combination with the smaller column inner diameter result in lower detection limits compared to the Dionex IonPac AS15-5μm column. The analytes are detected by suppressed conductivity with a Dionex ADRS™ 600 suppressor. This application note expands on work presented in Application Update 142, “Improved determination of trace anions in high purity waters by high-volume direct injection
Separation and quantification of ingredients and degradation products in coolants using IC-CD
This application note describes an IC-based method that uses a Thermo Scientific™ Dionex™ IonPac™ AS20 anion exchange column, an electrolytically generated potassium hydroxide eluent, and suppressed conductivity detection to determine oxalate in cromolyn sodium. The method proposed in this application note was validated following the guidelines outlined in USP General Chapter <1225>, Validation of Compendial Procedures.
This work uses IC with suppressed conductivity and mass spectrometry detection for organic acid determinations. This dual detection approach increases the information available from the sample. Samples were separated with a high-resolution Thermo Scientific™ Dionex™ IonPac™ AS11-HC-4μm column set using a Thermo Scientific™ Dionex™ Integrion™ HPIC™ system with suppressed conductivity detection, and an ISQ EC MS. Co-eluting organic acids can be accurately quantified with mass spectrometric detection, eliminating the need for the addition of methanol to the hydroxide eluent to enhance separation.
