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Displaying 1-5 of 10 results

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Trace analysis of pharmaceuticals and organic contaminants in water

Instrument Type: LCMSMS

We present the reliable and accurate quantitative analysis of contaminants at the pg/mL level in drinking water using the Thermo Scientific EQuan MAX Plus LC-MS system coupled to the Thermo Scientific TSQ Endura triple quadrupole mass spectrometer. Excellent reproducibility was shown for the target compounds in tap water using 1 mL injections at 0.37× maximum effluent concentration.

Forensic Screening for Drugs in Urine Using High-Resolution MS/MS Spectra and Simplified High-Performance Screening Software

Instrument Type: LCMSMS

Forensic toxicologists need an economical solution to screen for a virtually unlimited number of compounds in urine. Here we present a method for screening using a dilute-and-shoot approach with the Q Exactive Focus mass spectrometer and Thermo Scientific ToxFinder software. For forensic use only.

Quantitation of 122 Drugs in Urine by Triple Quadrupole Mass Spectrometry

Instrument Type: LCMSMS

Forensic toxicologists face an ever-expanding list of compounds for analysis. This note presents work done using a next-generation triple quadrupole mass spectrometer with fast SRM acquisition speed for quantitation of 122 analytes in a single chromatographic run, where scan speed does not impact sensitivity or quantitative performance. Compounds analyzed include opiates, opioids, benzodiazepines, barbiturates, amphetamines, tricyclic antidepressants, illicit compounds, and more. For forensic use only.

Detection of Pharmaceuticals, Personal Care Products, and Pesticides in Water Resources by APCI-LC-MS/MS

Instrument Type: LCMSMS

We developed a simple method for the simultaneous determination of trace levels of compounds from a diverse group of pharmaceuticals, pesticides, and personal care products using SPE and liquid chromatography-tandem mass spectrometry (LC-MS/MS). We determined which selected substances are present in significant quantities in the water resources around the Montreal region.

Analysis of Basic and Acidic Pharmaceutical Products in Drinking Water Using Online Sample Preparation and LC-MS/MS

Instrument Type: LCMSMS

We developed a robust analytical method for the analysis of 29 acidic and basic pharmaceutical residues in drinking water using online sample preparation. At the same time, we hope to reduce time spent on sample preparation and reduce opportunities for human error.