Five-fold increase in method throughput compared to original method (fifty samples/hour). Associated 10-fold reduction in cost per sample through reduced mobile phase consumption and waste generation. Additional reduced method complexity from easy-to-prepare mobile phase
Contaminants of emerging concern (CEC) in the environment are generally described as compounds that are unknown or unrecognized, undetected or not routinely monitored, and represent a diverse group of chemicals that may pose a risk to human health and the environment. Due to limited analytical capability and available resources , monitoring of CECs has been focused on selected analytes rather than a holistic approach. We describe a new analytical method that can be used in the quantitative analysis of 61 targeted and 312 non-targeted CECs.
We developed a simple method for the simultaneous determination of trace levels of compounds from a diverse group of pharmaceuticals, pesticides, and personal care products using SPE and liquid chromatography-tandem mass spectrometry (LC-MS/MS). We determined which selected substances are present in significant quantities in the water resources around the Montreal region.
We developed a robust analytical method for the analysis of 29 acidic and basic pharmaceutical residues in drinking water using online sample preparation. At the same time, we hope to reduce time spent on sample preparation and reduce opportunities for human error.
The Thermo Scientific HPLC system is applied for the determination of fenoprofen. The separation was performed on a Thermo Scientific Accucore RP-MS column, with a run time of 7 minutes and UV detection at 272 nm. The method of analysis is based on the USP monograph, and was scaled down by using an in-house method transfer calculator.