Contaminants of emerging concern (CEC) in the environment are generally described as compounds that are unknown or unrecognized, undetected or not routinely monitored, and represent a diverse group of chemicals that may pose a risk to human health and the environment. Due to limited analytical capability and available resources , monitoring of CECs has been focused on selected analytes rather than a holistic approach. We describe a new analytical method that can be used in the quantitative analysis of 61 targeted and 312 non-targeted CECs.
There is growing environmental concern regarding the health impact of trace levels of pharmaceuticals and personal care products (PPCPs) in water resources. In response, the U.S. Environmental Protection Agency (EPA) published Method 1694, which determines dozens of PPCPs in water, soil, sediment, and biosolids by HPLC-MS/MS. We demonstrate a progressive approach to analyzing PPCPs in environmental sources of water at the ng/L level with online sample preparation using small volumes of water, thus saving time and reducing the cost of analysis.
“Anti-infectives” is a general term that refers to several classes of biologically active compounds used to treat or prevent infections. Therapeutic agents such as anti - microbials (synthetic) and antibiotics (natural or semi-natural) are examples of anti-infectives. We describe a sensitive and robust method for the determination of some of the most prescribed anti-infectives in trace amounts (lower nanogram-per-liter range) in raw and treated wastewaters.
Antibiotics are widely used to treat diseased animals, prevent diseases and promote growth. However, inappropriate or excessive usage of antibiotics can result in antibiotic residues being found found in food and food products of animal origin. In here, a multi-residue, confirmatory method for the quantitative determination of antibiotics in chicken meat is described using the Thermo Scientific Transcend TLX system coupled to an LC-MS/MS. With online sample cleanup and high sample throughput, this approach addresses the demand for a fast and cost-effective multi-analyte method.
The use of LC-MS/MS for screening was described in a validated multi-residue screening method to monitor 58 antibiotics in milk.
