The aim of this application note is to demonstrate the performance of the Thermo Scientific™ TSQ™ 9610 triple quadrupole mass spectrometer coupled to the Thermo Scientific™ TRACE™ 1610 GC equipped with programmable temperature vaporizing injector (PTV) for the determination of trace level pesticide residues in baby food.
This work aimed to develop and validate an analytical method for simultaneous screening and quantification of pesticide residues in potato by using the QuEChERS extraction method in combination with the Thermo Scientific™ Exactive™ GC Orbitrap™ GC-MS system operated in full scan mode. The data acquisition and processing were carried out by using Thermo Scientific™ TraceFinder™ software. The optimized method was validated as per the SANTE/12682/2019 guidelines.
Optimization and validation of a multi-residue LC-MS/MS method for pesticides in spinach and cabbage by using Thermo Scientific Vanquish UHPLC and TSQ Quantis mass spectrometer. Sample preparation was performed using QuEChERS method that provided high recoveries for an extensive scope of pesticides in several simple steps. Data acquisition and processing were carried out using Thermo Scientific TraceFinder software. The optimized method was validated as per the SANTE guideline and applied to real samples demonstrating that the workflow is fit for purpose.
Multi-residue instrumental method that can be applied for high-throughput quantitation of pesticide residues in garlic and cumin at or below the current legislative requirements. The Thermo Scientific Orbitrap Exploris 120 mass spectrometer was operated in two different workflows: using full-scan Data-Independent Acquisition for quantitation and confirmation and using Thermo Scientific AcquireX intelligent data acquisition background exclusion workflow for full spectrum filtering, retrospective analysis, and multi-parameter-based compound identification.
In this study, the quantitative performance of the Thermo Scientific™ TSQ™ 9000 triple quadrupole GC-MS/MS system was assessed for the analysis of more than 200 pesticides in baby food at ultra low concentrations (as low as 0.025 μg/kg).
