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Quantitation of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3 in Plasma for Clinical Research Using the Prelude SPLC and TSQ Endura Mass Spectrometer
Description
LC-MS methods have been widely used to analyze vitamin D2 and vitamin D3 25-hydroxy metabolites (25OH D2 and 25OH D3) in human plasma. Clinical research laboratories are always seeking fast and cost-effective methods to improve analytical efficiency. Here we evaluated a high-efficiency, simple sample preparation method implemented on a Prelude SPLC system that combines online sample cleanup powered by Thermo Scientific TurboFlow technology with chromatographic separation and a TSQ Endura triple quadrupole mass spectrometer.| Market: | Clinical Research |
| Keywords: | 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, Prelude SPLC, TSQ Endura MS |
| Matrix: | Plasma |
| Author: | Xiaolei Xie and Marta Kozak |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
