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Quantitative Analysis of Methylmalonic Acid in Plasma Using a Q Exactive Focus High-Resolution Mass Spectrometer for Clinical Research

Description
Clinical research laboratories perform analysis of methylmalonic acid (MMA) using LC-MS because of that technique’s sensitivity and selectivity. Usually, the quantitative method is developed on a triple quadrupole mass spectrometer. Here we evaluated a method implemented on a Q Exactive Focus ultra-high resolution quadrupole-Orbitrap mass spectrometer for the best selectivity.Market: | Clinical Research |
Keywords: | Clinical Research, Methylmalonic acid (MMA), Q Exactive Focus |
Matrix: | Plasma |
Author: | Mindy Gao, Joe Di Bussolo, Marta Kozak |
Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.