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Quantitative Analysis of Methylmalonic Acid in Plasma Using a Q Exactive Focus High-Resolution Mass Spectrometer for Clinical Research Be the first to rate this application

quantitative analysis methylmalonic acid plasma using a q exactive focus highresolution mass spectrometer for clinical research

Description

Clinical research laboratories perform analysis of methylmalonic acid (MMA) using LC-MS because of that technique’s sensitivity and selectivity. Usually, the quantitative method is developed on a triple quadrupole mass spectrometer. Here we evaluated a method implemented on a Q Exactive Focus ultra-high resolution quadrupole-Orbitrap mass spectrometer for the best selectivity.
Market: Clinical Research
Keywords: Clinical Research, Methylmalonic acid (MMA), Q Exactive Focus
Matrix: Plasma
Author: Mindy Gao, Joe Di Bussolo, Marta Kozak
Affiliation: Thermo Fisher Scientific
Uploaded on 10/27/2016.

For Research Use Only. Not for use in diagnostic procedures.