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High-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring Buprenorphine and Norbuprenorphine in Urine
Description
Due to its increased abuse, forensic and testing labs test routinely for the presence of buprenorphine and its metabolite norbuprenorphine. To reduce their case backlog, these labs need cost-efficient analytical tests on hundreds of samples. We developed a high-throughput screening and quantitation LC-MS/MS method in which urine samples are quickly prepared and analyzed by a short chromatographic method implemented on a four-channel LC-MS system for improved productivity. For forensic use only.| Market: | Forensics; Toxicology |
| Keywords: | Urine, TSQ Quantiva, Forensic Toxicology, Transcend, Buprenorphine, norbuprenorphine, multi-channeling |
| Matrix: | Urine |
| Author: | Xiaolei Xie, Joe DiBussolo, Marta Kozak |
| Affiliation: | Thermo Fisher Scientific |
