High-Throughput, Cost-Efficient LC-MS/MS Forensic Method for Measuring Buprenorphine and Norbuprenorphine in Urine

Instrument Type: LCMSMS

Due to its increased abuse, forensic and testing labs test routinely for the presence of buprenorphine and its metabolite norbuprenorphine. To reduce their case backlog, these labs need cost-efficient analytical tests on hundreds of samples. We developed a high-throughput screening and quantitation LC-MS/MS method in which urine samples are quickly prepared and analyzed by a short chromatographic method implemented on a four-channel LC-MS system for improved productivity. For forensic use only.