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Quantitation of Seven Designer Cathinones in Urine Using Q Exactive Mass Spectrometer
Description
Substituted cathinones, or “Bath Salts,” have become the latest abused designer drugs. Based on cathinone, a substance found in the African Catha edulis (khat) plant, substituted cathinones are stimulants with amphetamine- and cocaine-like effects. We describe an HPLC-MS method for the forensic toxicological analysis of the three Schedule I cathinones: MDPV, methylone and mephedrone, as well as other substituted cathinones: methedrone, ethylone, butylone and naphyrone in urine with limits of quantitation (LOQs) of 0.5 ng/mL. For forensic use only.| Market: | Forensics; Toxicology |
| Keywords: | Bath salts, Urine, Quantitation, Accela HPLC, Forensic Toxicology, TraceFinder Software, Q Exactive Orbitrap MS, Cathinones |
| Matrix: | Urine |
| Author: | Marta Kozak, Kristine Van Natta, Shijun Sheng |
| Affiliation: | Thermo Fisher Scientific |
