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Faster separation of acidic and basic charge variants of Rituximab by Ion Exchange Chromatography using a shorter salt gradient method.
Description
The Thermo Scientific Dionex UltiMate 3000 LC Bio-LC system is applied for the Ion Exchange analysis of Rituximab. The separation was performed on a 3 micron Thermo Scientific MabPac SCX-10 column with a UV detection at 280 nm. With a run time of 16 minutes, the method allows easy separation of acidic and basic charge variants of RituximabMarket: | BioPharma |
Keywords: | HPLC, MAbPac, PDA detection, Rituximab, SCX |
Matrix: | N/A |
Author: | Manish Singh |
Affiliation: | Thermo Fisher Scientific, APAC CoE Lab, Ahmedabad, India |
For Research Use Only. Not for use in diagnostic procedures.