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Qualitative and Quantitative Analysis of Contaminants of Emerging Concern in Biosolids Using a Dilute and Shoot UHPLC-Orbitrap MS Method
Description
We develop an HRAM-based LC-MS/MS workflow to quantitatively analyze contaminants of emerging concern (CECs) in biosolids samples and to screen for 381 non-targeted CECs. Unlike LC-QQQ-MS/MS, the Fisher Scientific Exactive Plus Orbitrap full-scan high-resolution, accurate-mass (HRAM) mass spectrometry provides not only quantitative data for targeted compounds but also information on the non-targeted compounds, such as environmental transformation by-products, for possible environmental loadings and ecological effects that would not be available in a targeted assay.| Market: | Environmental |
| Keywords: | Pharmaceuticals, Environmental analysis, HRAM, TraceFinder Software, Exactive Plus MS, CEC, contaminants of emerging concern, degradation by-products, endocrine disrupting chemicals, personal care products, Pharmaceutical and Personal Care Products, sludge, Ultimate 3000 RS HPLC, LC-HRAM-MS/MS |
| Matrix: | Biosolids |
| Author: | Ahmed Mostafa, Shelly Bonte-Gelok, Charles Yang, Jonathan Beck, Dipankar Ghosh, Paul Yang |
| Affiliation: | Thermo Fisher Scientific; Ontario Ministry of the Environment-Canada; Ryerson University-Canada |
For Research Use Only. Not for use in diagnostic procedures.
