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Purity of the Liposomal Biotherapeutic Delivery Compound, DDAB, by HPLC-CAD Be the first to rate this application


Cationic Lipids are used as a transfection agent in biotechnological products created in the siRNA market space. As part of the lipid-based delivery system for these bio-therapeutic agents, their quality needs to be determined. DDAB, dimethyldioctadecylammonium bromide, is such a lipid, and using the Vanquish UHPLC with the universal Corona charged aerosol detector, many impurities were separated and can be quantified.
Market: BioPharma
Keywords: Cationic lipids, siRNA, DDAB, dimethyldioctadecylammonium
Matrix: Methanol / THF (1:1)
Author: Marc Plante
Affiliation: Thermo Scientific
Status: Proof of Concept
Uploaded on 1/18/2016.

For Research Use Only. Not for use in diagnostic procedures.