Rate
Ask the Expert
Suggest an Application
Add to Favorites
Create
Parts List
Parts List
Tell a
Friend
Friend
Print
PDF
Find methods for your needs
Purity of the Liposomal Biotherapeutic Delivery Compound, DDAB, by HPLC-CAD
Description
Cationic Lipids are used as a transfection agent in biotechnological products created in the siRNA market space. As part of the lipid-based delivery system for these bio-therapeutic agents, their quality needs to be determined. DDAB, dimethyldioctadecylammonium bromide, is such a lipid, and using the Vanquish UHPLC with the universal Corona charged aerosol detector, many impurities were separated and can be quantified.Market: | BioPharma |
Keywords: | Cationic lipids, siRNA, DDAB, dimethyldioctadecylammonium |
Matrix: | Methanol / THF (1:1) |
Author: | Marc Plante |
Affiliation: | Thermo Scientific |
Status: | Proof of Concept |
For Research Use Only. Not for use in diagnostic procedures.