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AN1073: Determination of Ammonia in Sodium Bicarbonate Be the first to rate this application

ic determination ammonia


This study describes an ion chromatography (IC)-based method for the determination of ammonia (as ammonium) in sodium bicarbonate. The method performance characteristics—linearity, precision, accuracy, ruggedness, and the limits of detection (LODs) and quantitation (LOQs)—were measured according to the requirements described in the USP General Chapter <1225> guidelines. The automation features such as the electrolytically generated mobile phase and self-regenerating suppressor contribute to the robustness and sensitivity of this method.
Market: Pharma
Keywords: Monograph, USP, ammonium, Dionex IonPac CS16 Column, Hemodialysis Solution, High-Capacity Cation-Exchange Column, Ion Chromatography, Reagent-Free Ion Chromatography, RFIC Suppressed Conductivity, Sodium Bicarbonate
Matrix: Drug
Author: Lipika Basumallick and Jeffrey Rohrer
Affiliation: Thermo Fisher Scientific
Uploaded on 3/16/2015.

For Research Use Only. Not for use in diagnostic procedures.