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AN194: Determination of Carbachol In Ophthalmic Solutions Using a Reagent-Free Ion Chromatography System
Description
A simple RFIC method is described for determination of carbachol, bethanechol, and choline in 25 min with a Dionex IonPac CS17 column. Methanesulfonic acid (MSA) eluent is delivered isocratically by an Eluent Generator (EG). Use of an EG eliminates eluent preparation errors and helps ensure retention time reproducibility. The sensitivity of suppressed conductivity detection allows carbachol determination in ophthalmic solutions with only a simple sample dilution.| Market: | Pharma |
| Keywords: | 2-hydroxypropyltrimethylammonium chloride, Bethanechol, Cholinergic agent, Glaucoma, IonPac CS17, RFIC, USP 29-NF 24 |
| Matrix: | Water |
| Author: | Pranathi Perati and Jeff Rohrer |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
