AN117: Quantification of Carbohydrates and Glycols in Pharmaceuticals - Alditols and Small Carbohydrates Method

Instrument Type: IC

Two oral, over-the-counter medications were evaluated as representative pharmaceutical products. A cough suppressant and a multisymptom cold/flu medication were chosen because they contain a complex mixture of simple sugars, glycols,and sugar alcohols. These carbohydrates and glycols are also commonly found in other medications. This method uses the CarboPac MA1 column to retain and separate the target analytes.

AN117: Quantification of Carbohydrates and Glycols in Pharmaceuticals - Small Sugars

Instrument Type: IC

This application note describes the use of three different anion-exchange columns with amperometric detection to analyze common simple sugars, sugar alcohols, and glycols in pharmaceutical formulations. This record describes a method using the CarboPac PA10 column to determine some of the target carbohydrates. The reader is advised to review TN21 for updated waveform information.

AN117 - Quantification of Carbohydrates and Glycols in Pharmaceuticals - Glycols Method

Instrument Type: IC

This application note describes the use of three different anion-exchange columns with amperometric detection to analyze common simple sugars, sugar alcohols, and glycols in pharmaceutical formulations. The method in this entry shows how to determine glycols using ion-exclusion chromatography on Dionex ICE-AS1 column.

Improved analysis of components of a cold remedy using a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of cold remedy components. The separation is performed on a Thermo Scientific Hypersil GOLD HPLC column, with UV detection at 280 nm.