Fast and Ultrafast LC-MS/MS Methods for Robust and Reliable Analysis of Pesticides in Food Using the Vanquish UHPLC System

Instrument Type: LCMSMS

Food safety is an increasing concern that has resulted in stringent pesticide regulation globally and in continuous recalls of food products. Food safety regulations require the screening and the quantitation of a large number of pesticides in food at maximum residue levels generally set in the ppb-ppm range to minimize their possible negative effects on human health. Here we present a comparison between fast and ultrafast LC-MS/MS methods in timed SRM mode for the analysis of 250+ pesticides in food extracts. The two methods were compared in terms of analysis time and data quality.

UHPLC Method Development for Simultanous Determination of Antihypertensive Combination Agents

Instrument Type: UHPLC

The current trend in antihypertensiion therapy is the medication with several antihypertension agents in a single pill. Here eluent switching capabilities of the Thermo Scientific Vanquish Binary pump H are applied to develop a UHPLC method for simultanous determination of antihypertensive combination agents on a Thermo Scientific Accucore Vanquish C18+ column by scouting different eluent combinations.