Related substances analysis of Pregabalin on solid dosages

Instrument Type: UHPLC

The Thermo Scientific™ Dionex™ UltiMate 3000 LC system is applied for a related substance analysis of pregabalin. The separation was performed on a Thermo Scientific Accucore PFP 2.6 µm HPLC column with UV detection.

Rapid determination of Pregabalin in human plasma by SPE-LC-MS/MS using Thermo Scientific SOLA SCX mixed mode SPE cartridges and a Thermo Scientific Accucore PFP HPLC column

Instrument Type: LCMSMS

A simple, rapid and sensitive procedure for the determination of pregabalin in human plasma by LC-MS/MS was developed and evaluated. The drug was isolated from a plasma matrix using Thermo Scientific SOLA SCX solid phase extraction material, and the components of the resultant extracts were separated on a Thermo Scientific Accucore PFP HPLC column. Detection was performed on a triple quadrupole mass spectrometer. For Research Use Only. Not for use in diagnostic procedures.