High-Resolution Accurate-Mass (HRAM) Phthalate Screening using Direct Analysis in Real Time (DART) Ambient Ionization

Instrument Type: MSMS

Phthalic acid diesters (PAEs), or phthalates, are widely used in industry as a plasticizer in products like toys, flooring, personal care products and food packages. Some PAEs are classified as hazardous, affecting mainly the reproductive system and possibly contributing to cancer. Though regulated, these phthalates might be present and used during production of goods. We demonstrate the possibility of using precursor ion selection and full scan MS2 spectrum, and utilize it as a fingerprint for the characterization of the different compounds/isomers with nominal m/z ratios 279 and 391.

Detection and Quantitation of Brominated and Chlorinated Hydrocarbons by DART with Linear Ion Trap and Triple Quadrupole Technology

Instrument Type: MSMS

Brominated hydrocarbons (BFRs) have been used in various industries for decades. Most chlorinated pesticides (OCs) have been banned in the United States, but their use still occurs in developing countries. The persistence of BFRs and OCs in the environment, potential deleterious activity, makes the detection and monitoring of these compounds an important topic. We propose DART as a simple, rapid, easy-to-use technique; eliminating the need for chromatographic method development, and reducing or eliminating sample preparation, for detection and quantitation of both BFRs and OCs.