Related substances analysis of Cefazoline using a C18 type HPLC column folowing EP 8.1 Monograph

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the related substances analysis for Cefazolin as per EP. The analysis was performed on a Thermo Scientific Hypersil Gold HPLC column using the method described in the EP 8.1 Monograph. The results obtained for resolution met the criteria as per EP. The results obtained for the resolution between Cefazolin & impurity L is found to be 5.3 (EP criteria is NLT 2.0).

Fast analysis of cephalosporins using a Thermo Scientific Syncronis aQ HPLC column

Instrument Type: HPLC

The Thermo Scientific UltiMate 3000 HPLC system is applied for the determination of cephalosporins. The separation is performed on a Thermo Scientific Syncronis C18 HPLC column, with UV detection at 254 nm.

Improved analysis of antibiotics using a Thermo Scientific Hypersil GOLD HPLC column

Instrument Type: HPLC

The Thermo Scientific HPLC system is applied for the analysis of antibiotics. The separation is performed on a Thermo Scientific Hypersil GOLD HPLC column, with UV detection at 254 nm.