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Displaying 1-4 of 4 results for Tag: Basic Drug
Fast isocratic method for the separation of basic drugs
Instrument Type: HPLCThe Thermo Scientific HPLC system is applied for the analysis of basic drugs. The separation is performed on a Thermo Scientific Acclaim 120 C18 column, with UV detection at 220 nm. This application is used as a routine lot qualification test for the Acclaim 120 C18 column stationary phase. Low silanol activity preserves the good peak shape for amitriptyline as the sample concentration decreases (amitriptyline mass for trace A is 1200 ng, for trace B is 400 ng, and for trace C 94 ng).
Rapid determination of Minoxidil using the Thermo Scientific Acclaim Mixed-Mode WCX-1 HPLC column
Instrument Type: HPLCThe Thermo Scientific Acclaim Mixed-Mode WCX-1 column is used for the fast analysis of minoxidil in formulation with a run time of less than 3 minutes.
Simultaneous analysis of the basic drug Trimipramine and its counterion using the Thermo Scientific Acclaim Mixed-Mode WAX-1 HPLC column
Instrument Type: HPLCThe Thermo Scientific Acclaim Mixed-Mode WAX-1 retains trimipramine, a hydrophobic base, by reversed-phase interaction, and maleate, the hydrophilic counterion, by anion-exchange interaction. In this way, it can eliminate a separate test for the two components.
Rapid LC-MS/MS method for the determination of Sildenafil from plasma using a Thermo Scientific Accucore RP-MS HPLC column
Instrument Type: LCMSMSThe Thermo Scientific HPLC system is applied for the analysis of Sildenafil (Viagra) in plasma. The separation was performed on a Thermo Scientific Accucore RP-MS HPLC column in under 5 minutes, with MS/MS detection. For Research Use Only. Not for use in diagnostic procedures.
