A Strategy for an Unknown Screening Approach on Environmental Samples Using HRAM Mass Spectrometry

Instrument Type: LCMS

The analysis of food and environmental samples for contaminants by LC-MS has become a quick and cost-effective routine application when run in a targeted fashion, but this method disregards events or circumstances not taken into account beforehand. We describe a method by one data set can serve for routine high throughput quantitative analysis and for versatile non-targeted investigations in a highly automated manner.

Routine, Targeted and Non-Targeted Analysis of Environmental Contaminants of Emerging Concern - Development and Validation of a UHPLC Orbitrap MS Method

Instrument Type: LCMS

Contaminants of emerging concern (CEC) in the environment are generally described as compounds that are unknown or unrecognized, undetected or not routinely monitored, and represent a diverse group of chemicals that may pose a risk to human health and the environment. Due to limited analytical capability and available resources , monitoring of CECs has been focused on selected analytes rather than a holistic approach. We describe a new analytical method that can be used in the quantitative analysis of 61 targeted and 312 non-targeted CECs.