The Thermo Scientific HPLC system is applied for the analysis of basic drugs. The separation is performed on a Thermo Scientific Acclaim 120 C18 column, with UV detection at 220 nm. This application is used as a routine lot qualification test for the Acclaim 120 C18 column stationary phase. Low silanol activity preserves the good peak shape for amitriptyline as the sample concentration decreases (amitriptyline mass for trace A is 1200 ng, for trace B is 400 ng, and for trace C 94 ng).

The Thermo Scientific HPLC system is applied for the determination of five antidepressants. The separation is performed on a Thermo Scientific Acclaim PolarAdvantage (PA) HPLC column, with UV detection at 220 nm.

The Thermo Scientific HPLC system is applied for the separation of basic compounds. The separation was performed using a Thermo Scientific Accucore RP-MS column in under 3 minutes, with UV detection at 215nm.

The Thermo Scientific HPLC system is applied for the determination of tricyclic antidepressants. The samples are prepared using Thermo Scientific SOLA CX solid phase extraction (SPE) cartridges, and the separation performed on a Thermo Scientific Hypersil GOLD HPLC column. For Research Use Only. Not for use in diagnostic procedures.

The Thermo Scientific HPLC system is applied for the analysis of bases from human plasma and urine. The samples are prepared using Thermo Scientific SOLA CX solid phase extraction (SPE) cartridges, and the separation is performed on a Thermo Scientific Accucore RP-MS HPLC column, with UV detection at 254 nm. For Research Use Only. Not for use in diagnostic procedures.