PFAS are per- and polyfluoroalkyl substances. The chemical nature of the C-F bonds makes these compounds extremely stable. Hence, PFAS have been given the term “forever compounds”. This application note will present data for measuring 40 PFAS in fortified water samples following the third draft of EPA Method 1633. An MDL study was conducted in reagent water to demonstrate that equivalent or better performance can be attained using the Thermo Scientific™ Vanquish™ Flex Binary UHPLC system and Thermo Scientific™ TSQ™ Quantis Plus mass spectrometer.

This application demonstrated an improved method for the determination of tetrafluoroborate, perchlorate, and hexafluorophosphate in simulated lithium-ion battery production samples using a RFIC system with suppressed conductivity detection, and 2 mm versions of Dionex IonPac AS20 columns. This method significantly reduces eluent consumption and thus prolongs the life of the EGC as flow rate is reduced from 1.2 to 0.3 mL/min. The method has a linear calibration over the concentration range of 1 to 40 mg/L and was shown to be precise and accurate.

The European Food Safety Authority (EFSA) reported chlorate as a risk to human health. In June 2020, the European Commission set chlorate limits for various foods, including the limit for algae (0.05 mg/kg). This work describes a straightforward method to determine chlorate in seaweed-derived agar products. A sample preparation circumvents unwanted gelation, thus avoiding clogging capillaries and columns. Our approach is suitable for analyzing chlorate where the final agar content does not exceed 0.5–1.0%

The goal of this work is to evaluate and identify cation-exchange columns suitable for applications involving quaternary amine compound (QAC) determinations. Four Thermo Scientific Dionex IonPac columns (CS17, CS19-4µm, CS20, and CS21-4µm) were evaluated. A Thermo Scientific™ Dionex™ ICS-5000+ HPIC™ system that produced an electrolytically generated methane sulfonic acid (MSA) eluent was used for this work. The results for retention time, peak area, peak asymmetry, and efficiency are included here along with recommendations for choosing a column for QAC determinations.

This record presents a fast isocratic method to determine citric acid in carbonated beverages with a carbonate-based eluent and electrolytically regenerated suppression. This application can be run on any Thermo Scientific™ Dionex™ IC system equipped with suppressed conductivity detection. The carbonate eluent (see Method) can be generated electrolytically using Thermo Scientific™ Dionex™ RFIC™ technology.