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Displaying 1-5 of 90 results for: columns

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Robust peptide quantitation using the TSQ Certis triple quadrupole mass spectrometer and OptiSpray ion source and cartridges

Instrument Type: nanoLCMS

This work demonstrated quantitative targeted peptide analysis using the TSQ Certis triple quadrupole mass spectrometer coupled with the Vanquish Neo UHPLC system. With the OptiSpray ion source and cartridge columns optimized for nano- and capillary flow (<5 µL/min), the platform delivered strong reproducibility, retention time stability, and sensitivity for an 82-peptide plasma biomarker panel.

AN003548 Fast analyses of anions in water with microbore columns using a compact ion chromatography system for reduced eluent use

Instrument Type: IC

Industries are adopting methods to enhance analytical performance while minimizing ecological impact. In ion chromatography, using microbore columns with diameters of 2 mm or less reduces eluent use, cutting hazardous waste and improving throughput.This note highlights rapid anion analysis in water using microbore column, which significantly reduces liquid waste compared to standard bore columns. This method enhances safety and sustainability by minimizing waste production.Both chemical and electrolytic suppression techniques are demonstrated.

Maximizing sample throughput and sensitivity in nano and capillary LC-MS: Harnessing a tandem direct injection workflow and a dual-spray ion source

Instrument Type: nanoLCMS

Exploring the potential of a novel, intelligent tandem LC-MS workflow with near 100% MS utilization from deep-dive and high-throughput proteomics.

A dual-column, single-spray configuration for capillary and micro-flow LC-MS applications

Instrument Type: LCMS

Demonstrating a tandem LC-MS configuration for high-throughput proteomics and peptide quantification with near 100% MS utilization.

AN002338: Quantitation of per- and polyfluoroalkyl substances (PFAS) in aqueous samples by LC-MS/MS following EPA Draft Method 1633

Instrument Type: LCMS

PFAS are per- and polyfluoroalkyl substances. The chemical nature of the C-F bonds makes these compounds extremely stable. Hence, PFAS have been given the term “forever compounds”. This application note will present data for measuring 40 PFAS in fortified water samples following the third draft of EPA Method 1633. An MDL study was conducted in reagent water to demonstrate that equivalent or better performance can be attained using the Thermo Scientific™ Vanquish™ Flex Binary UHPLC system and Thermo Scientific™ TSQ™ Quantis Plus mass spectrometer.