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Displaying 1-5 of 9 results for: Amoxicillin

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The VetDrugs Explorer Collection: screening and quantitation of multi-class veterinary drug residues in animal matrices with a comprehensive workflow solution

Instrument Type: LCMSMS

A robust, sensitive, and reliable multi-residue LC-MS/MS method workflow solution that uses the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer provides analysis and quantitation of more than 160 veterinary drugs with the Thermo Scientific VetDrugs Explorer Collection solution in salmon (fillet), bovine muscle, and milk. The complete instrument and data processing method including SRM settings is included with the VetDrugs Explorer Collection start-to-finish workflow solution. In 17 minutes, the target veterinary drugs were detected and quantified in food matrices.

Assay analysis of Amoxicillin and Clavulanate Potassium as per USP

Instrument Type: HPLC

The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the analysis of Amoxicillin and Clavulanate Assay as per USP. The analysis was performed on a Thermo Scientific Syncronis aQ L1 HPLC column using the method described in the USP 40 monograph. The results obtained were found to be within acceptance criteria as stated in the USP. Resolution between Amoxicillin and clavulanic acid was 14.0 (USP criteria: not less than 3.5). Tailing Factors observed were 0.84 & 1.25 respectively (USP criteria: not more than 1.5 for each analyte). RSD found to be less than 2% for both analytes

Determination of a Single Methodology for the Analysis and Quantitation of Multiclass Veterinary Drugs in Different Animal Matrices Used for Consumption

Instrument Type: LCMSMS

Veterinary drugs are pharmacologically active compounds that can result in non-desirable drug residues in the food chain. Animals with high amounts of these drugs can cause harm in humans or can render the use of antibiotics useless due to the counter effects of the drugs. The quantification of over 200 multi-class veterinary drugs from different meat products usually involves time consuming extraction methods with either SPE or LLE. We describe a robust method, utilizing a single LC-MS/MS run to quantitate over 200 veterinary drugs in a variety of matrices.

Rapid Screening Method for Veterinary Antibiotics Using an Advanced Solid Core UHPLC Column and UHPLC System with MS/MS Detection

Instrument Type: LCMSMS

There is increasing demand to provide rapid and selective screening techniques for a wide range of antibiotic drugs. Their abuse as a feed supplement in food animals is of growing concern and is subject to regulations globally. Creating screening methods for multiple analytes is more cost effective than dedicated methods for fewer analytes. This application shows the advantages of using the Thermo Scientific Accucore Vanquish C18 UHPLC 1.5 µm column and Vanquish UHPLC system for the analysis of thirty-six antibiotics.

Variable Data-Independent Acquisition (vDIA) Delivers High Selectivity and Sensitivity in Combined Targeted and Untargeted Analyses for Small Molecules

Instrument Type: LCMSMS

Forty-four multi-class veterinary drugs of known concentrations were employed to demonstrate how the use of a generic variable data-independent acquisition (vDIA) method with wide MS/MS precursor isolation windows achieves sensitivity and selectivity comparable to data-dependent MS2 acquisition (using narrow isolation windows) in quantitative and qualitative small molecule applications. In addition, a full record of MS and MS/MS data for the measured sample fit for non-targeted and unknown screening purposes is delivered. vDIA is not available in the United States of America