A robust, sensitive, and reliable multi-residue LC-MS/MS method workflow solution that uses the Thermo Scientific TSQ Altis triple quadrupole mass spectrometer provides analysis and quantitation of more than 160 veterinary drugs with the Thermo Scientific VetDrugs Explorer Collection solution in salmon (fillet), bovine muscle, and milk. The complete instrument and data processing method including SRM settings is included with the VetDrugs Explorer Collection start-to-finish workflow solution. In 17 minutes, the target veterinary drugs were detected and quantified in food matrices.
Phenylbutazone (bute, PBT) is one of the most widely used (non-steroidal) anti-inflammatory (NSAiD) and painkiller drug for dogs and horses. Horse meat is still widely used for human consumption in some European countries. For those animals marked for human consumption, a limited number of medicines can be administered. A newly developed LC-MS/MS method for the determination of PBT in horse meat with LC-MS/MS is described here. The method was validated in-house and its applicability for routine testing was tested following the European legislation requirements.
We developed a highthroughput, sensitive and precise screening method, with minimal sample preparation, for the determination of multiclass antibiotic residues in milk samples by LC-MS/MS.
