To demonstrate practical approaches that can be used to significantly improve throughput of the ibuprofen USP assay monograph keeping to the spirit o USP-NF Chapter <621> guidelines while maintaining USP quality acceptance criteria. To then take this optimized assay monograph and reduce analysis time even further.
We present the reliable and accurate quantitative analysis of contaminants at the pg/mL level in drinking water using the Thermo Scientific EQuan MAX Plus LC-MS system coupled to the Thermo Scientific TSQ Endura triple quadrupole mass spectrometer. Excellent reproducibility was shown for the target compounds in tap water using 1 mL injections at 0.37× maximum effluent concentration.
Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) detected in surface and drinking waters, as well as in treated wastewater. They are an issue of increasing international attention due to potential environmental impacts. We developed an analytical method capable of determining PPCPs and their by-products in wastewater treatment plant (WWTP) samples. This workflow was applied in a survey of 35 permeate samples obtained from a pilot anaerobic membrane bioreactor (AnMBR).
Demonstration of the advantages of using the Thermo Scientific Accucore XL C18 4 μm UHPLC column and the Thermo Scientific Vanquish UHPLC system for the separation of ibuprofen, ibuprofen-related compound C, and valerophenone.
In this work the advantages of using the Thermo Scientific Accucore Vanquish C18+ 1.5 μm UHPLC column and the Thermo Scientific Vanquish UHPLC system for the separation of ibuprofen, ibuprofen-related compound C, and valerophenone were demonstrated. The advanced capabilities of the Vanquish UHPLC system allow the Accucore Vanquish UHPLC columns to be operated at higher flow rates that enable development of rapid analytical methods while maintaining performance.
