We present a multi-residue instrumental method that can be applied for high-throughput screening and semi-quantitation of pesticide residues in food matrices at or below the current legislative requirements. A high-resolution, accurate-mass mass spectrometer operated in Full Scan – Variable Data-Independent Analysis (FS-vDIA)* mode provided an option for full spectrum filtering, retrospective analysis, and multi-parameter-based compound identification. The method was validated for 328 target pesticides, with an option for the future extension to a larger number. (*vDIA not available in US.)
In this study, a fast, easy, and robust workflow was used to analyze pesticide residues in baby food. Accurate and sensitive detection, quantification, and identification of pesticides in baby foods is of particular importance because babies are more vulnerable to adverse health effects from these chemicals.