We present a reliable and cost-effective IC-MS/MS multi-residue method for high-throughput screening and quantitation of polar pesticide residues and their metabolites in food matrices below the current legislative requirements. In contrast to methods described in the literature, sample preparation is simplified and the use of ion chromatography speeds up the separation.
We present a sensitive, robust, fast method to determine and quantify residues of polar pesticides in food samples in complex matrices at required regulatory levels. The Thermo Scientific UltiMate 3400 RSLC system is used in combination with a Thermo Scientific TSQ Quantiva triple quadrupole mass spectrometer to analyze QuPPe method extracts. The robustness of the system allows uninterrupted analysis of up to 500 honey samples and easy cleaning of the ion introduction system.