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Rapid LC-MS/MS analysis of Montelukast in human plasma using Thermo Scientific SOLA SAX SPE and a Thermo Scientific Accucore C8 HPLC column Be the first to rate this application

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2
00.30.60.91.21.5Time [min]-20020406080100Response [mVolts]
# Compound Name Compound Class RT (min)
1 Isomer Isomer 1.06
2 Montelukast Asthma drug 1.16

Description

The Thermo Scientific Dionex UltiMate 3000 HPLC system is applied for the analysis of montelukast in human plasma. The samples were prepared using a SOLA SAX solid phase extraction (SPE) 96 well plate, and the separation performed in under 1.5 minutes on a Thermo Scientific Accucore C8 HPLC column, with MS/MS detection. The dynamic range was linear between 1 and 1000ng/mL with a R² of 0.9901. For Research Use Only. Not for use in diagnostic procedures.
Market: Pharma
Keywords: Accucore C8, LC-MS/MS, Montelukast, MS detection, SOLA SAX, SPE
Matrix: Human plasma
Uploaded on 1/10/2013.

For Research Use Only. Not for use in diagnostic procedures.