Rate
Ask the Expert
Suggest an Application
Add to Favorites
Download eWorkflow
CreateParts List
Tell a Friend
PrintFind methods for your needs
USP 38 monography - assay of lovastatin related compound A using a C8 HPLC column
1
2
| # | Compound Name | Compound Class | RT (min) |
|---|---|---|---|
| 1 | Lovastatin | Statin | 6.56 |
| 2 | Lovastatin Related Compound-A | Impurity | 9.14 |
Description
The Thermo Scientific Dionex UltiMate 3000 LC system is applied for the assay analysis of lovastatin related compound-A. The analysis was performed on a Thermo Scientific Syncronis C8 HPLC column using the method described in the USP 38 monograph. Resolution between lovastatin and lovastatin related compound A was 10.9 (exceeded USP criteria of NLT 6.0). Relative retention time of lovastatin related compound A with respect to lovastatin was 1.39 (met USP criteria of about 1.3). The % RSD for replicate injection of standard solution was 0.9% (exceed USP criteria not more than 5.0%).| Market: | Pharma |
| Keywords: | HPLC, Syncronis C8, UV detection, USP 38 monograph, Lovastatin |
| Matrix: | N/A |
| Author: | Manish Singh |
| Affiliation: | Thermo Fisher Scientific |
For Research Use Only. Not for use in diagnostic procedures.
