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AN259: Determination of N-Methylpyrrolidine in Cefepime with Nonsuppressed Conductivity Detection
![an259 determination nmethylpyrrolidine cefepime with nonsuppressed conductivity detection](/Image/AppImage/1860/20161114171543/an259-determination-nmethylpyrrolidine-cefepime-with-nonsuppressed-conductivity-detection?imageNameOnDisk=1860.png)
Description
This work describes the determination of N-Methylpyrrolidine by cation-exchange chromatography with non-suppressed conductivity detection. This method is different from the one described in AN199, which uses suppressed conductivity. The results shown here meet the USP criteria for Organic Impurities, Procedure 1 (Limit of N-Methylpyrrolidine) in the proposed methods for cefepime hydrochloride and Cefepime for Injection.Market: | Pharma |
Keywords: | AN 259, IonPac SCS1, NMP, USP |
Matrix: | N-Methylpyrrolidine |
For Research Use Only. Not for use in diagnostic procedures.