AN105: Glycosylation Analysis of Human Serum Transferrin Glycoforms Using Pellicular Anion-Exchange Chromatography

Instrument Type: IC

Variation of glycoprotein sialylation has significant clinical implications. For example, human serum transferrin (HST) of cancer, rheumatoid arthritis, and haemochromatosis patients show an increased level of HST sialylation; whereas patients with heavy alcohol consumption show a high incidence of asialo glycoforms. Here we show separation of those glycoforms.