AN2967: Implementation of a Walk-Up High-Pressure Capillary Ion Chromatograph for the Fast Separation of Pharmaceutical Relevant Inorganic Cations (pain relief tablet)

Instrument Type: IC

The counter ion impacts the API drug’s efficacy, solubility, and toxicity, and therefore counter ion determinations are important to pharmaceutical companies during all stages of product development and as part of product quality monitoring. In this example, the sodium counter ion is determined in a water extract of a pharmaceutical drug tablet designed for pain relief. Here fast sodium determinations were demonstrated on an IonPac CS12A-8µm capillary column using a walk-up high pressure capillary IC system.