Structural Determination of Flavonoids Using MSn

Instrument Type: LCMSMS

Flavonoids, a class of polyphenolic compounds found in tea, plants and many fruits, have shown some promising results related to anti-cancer as well as anti-inflammatory and anti-allergy properties. For these reasons, there has been renewed interest in both detecting and characterizing these compounds. We demonstrate the utility of MSn for structural determination and unambiguous classification of a suspected flavonoid compound and unambiguous determination of product origin.

AU164: Determination of Glucosamine in Chondroitin Sulfate-Containing Dietary Supplements Using HPAE-PAD

Instrument Type: IC

Glucosamine (GlcN), a major structural component of glycosaminoglycan compounds, and chondroitin sulfate (CS), a glycosaminoglycan, are involved in normal joint function and are sold as dietary supplements for joint health. Accurate determinations of GlcN in dietary supplements by HPAE-PAD were reported in AN197. In AN197 the dietary supplements analyzed did not contain CS, a polyanionic polysaccharide that has the potential to overload the column and compromise GlcN determinations. This application update extends the determination of GlcN to dietary supplements containing CS.

Aristolochic acids

Instrument Type: HPLC-CAD

Aristolochic acids in Aristolochia fangchi extract are separated within 15 min on a Thermo Scientific™ Accucore™ C18 column and detected by the Thermo Scientific™ Dionex™ Corona™ Veo™ RS charged aerosol detector.