AN117: Quantification of Carbohydrates and Glycols in Pharmaceuticals - Alditols and Small Carbohydrates Method

Instrument Type: IC

Two oral, over-the-counter medications were evaluated as representative pharmaceutical products. A cough suppressant and a multisymptom cold/flu medication were chosen because they contain a complex mixture of simple sugars, glycols,and sugar alcohols. These carbohydrates and glycols are also commonly found in other medications. This method uses the CarboPac MA1 column to retain and separate the target analytes.

AN117: Quantification of Carbohydrates and Glycols in Pharmaceuticals - Small Sugars

Instrument Type: IC

This application note describes the use of three different anion-exchange columns with amperometric detection to analyze common simple sugars, sugar alcohols, and glycols in pharmaceutical formulations. This record describes a method using the CarboPac PA10 column to determine some of the target carbohydrates. The reader is advised to review TN21 for updated waveform information.

Determination of artificial sugars in cough drops using a simple HILIC method

Instrument Type: HPLC-CAD

The Thermo Scientific Acclaim Trinity P2 used in HILIC mode separated malitol and isomalt in cough drops using a simple HILIC method.